DoseRider: Dose-Response Analysis Tool

Configure your dose-response analysis

Adjust the settings below to custom your analysis of dose-response analysis. Set parameters like feature sets, size filters, and transformation options to refine your results. Once configured, click "Submit" to begin.

Dataset summary

Name:	PRJNA869442 - D-8 - homo_sapiens - RNA-seq - 2024-09-16 09:40:31.681577+00:00
Doses/Concentrations:	0,5.00e-04,1.00e-03,1.00e-02,1.00e-01,5.00e-01,1.00e+00,5.00e+00,1.00e+01
Dose/Concentration units:	µM
Omics type:	RNA-seq
Feature annotation:	symbols
Number of samples:	52
Species:	Homo sapiens

Feature sets field

Custom gmt file
Upload custom GMT file:
Feature set database:
Minimum set size:
Maximum set size:
Avoid feature sets (proteins, genes, metabolites) with antagonistic effects by applying the First Principal Component (PC1).

Data preprocessing

Log-transform dose/concentration values. This is recommended for doses/concentrations selected in logarithmic increments

Log-transform intensity values. This is recommended for intensity values that are not normally distributed.

Models fitting:

Linear

Non-linear (Fixed)

Non-linear (Mixed)

Viability analysis

Viability analysis
Viability Column: