Pathway Details: ABC-family proteins mediated transport
Geneset Dose-Response Model
The table shows the best dose-response fitted model for the ABC-family proteins mediated transport geneset. The results include the best model p-value, AICc, BIC, and optimal clusters. These metrics indicate the statistical significance and model fit. Full explanations and specific results can be found in the FAQ section.
Click on the tabs below to view the plots for the gene random effect relationship, gene heatmap, and pathway responses.
| Geneset | Geneset Set Size | Genes in gene set | Best Model | Best Model P-value | Best Model Adjusted P-value | Best Model AICc | Best Model BIC | Optimal Clusters | BMD Lower 95 CI | Mean BMD | BMD Upper 95 CI | TCD1 Lower 95 CI | TCD1 Mean | TCD1 Upper 95 CI |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ABC-family proteins mediated transport | 58 | 20 | Non-linear mixed model | <0.001 | <0.001 | 159 | 268 | 2 | nan | nan | nan | nan | nan | nan |
Pathways level visualizations
Representation of the detailed visualizations for the selected pathway/geneset from the analysis with DoseRider. These visualizations focus on the pathway geneset proteins, genes, or metabolites. The available plots include: heatmap from the normalization values, random effect distribution, and pathway dose-response predicted values.
Click on the tabs below to view the plots for the gene random effect relationship, gene heatmap, and pathway responses.